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MOSINTER GROUP LIMITED
MOSINTER GROUP LIMITED

China Prednisolone CAS 50-24-8 HYDRODELTALONE manufacturer

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Prednisolone CAS 50-24-8 HYDRODELTALONE 

Place of Origin: Zhejiang, China (Mainland) 
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Product Detail

Model No.: MOS8
Packing: As per request of clients
Name: Prednisolone
Molecular Formula: C21H28O5
Content: 98%min
refractive index: 100 ° (C=1, Dioxane)
Synonyms 2: HYDRODELTALONE
Production Capacity: 200KG/MONTH
Delivery Date: within 7 days
CAS: 50-24-8
Molecular Weight: 360.44
Brand: MOSINTER
Melting point: 240 °C (dec.)(lit.)

Steroids;Steroids & Hormones - 13C & 2H;Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Intermediates & Fine Chemicals

Prednisolone CAS 50-24-8  HYDRODELTALONE

Chemical Properties

Crystalline Solid

Usage

Synthetic corticosteroid; metabolically interconvertible with prednisone

Usage

glucocorticoid

Usage

substance P antagonists (SPA). It mediates its effect by acting on neurokinin 1 receptor

Definition

ChEBI: A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

 

Prednisolone Preparation Products And Raw materials

 

Preparation Products

[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate-->11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-methanesulphonate

Raw materials

Hydrocortisone

 


Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers.Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, andmultiple sclerosis. It is used by mouth, injection into a vein, as a skin cream, and as eye drops.

Side effects with short term use include nausea and feeling tired. More severe side effects include psychiatric problems, which may occur in about 5% of people.[4] Common side effects with long term use include bone loss, weakness, yeast infections, and easy bruising. While short term use in the later part of pregnancy is safe, use long term or early in early pregnancy is occasionally associated with harm to the baby. It is aglucocorticoid made from hydrocortisone (cortisol).

Prednisolone was discovered and approved for medical use in 1955. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication.The wholesale cost in the developing world is about 0.01 to 0.02 USD per day.



Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and autoimmune conditions such as asthma, uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis,pericarditis, temporal arteritis and Crohn's disease, Bell's palsy, multiple sclerosis, cluster headaches, vasculitis, acute lymphoblastic leukemia and autoimmune hepatitis, systemic lupus erythematosus, Kawasaki disease, dermatomyositis,and sarcoidosis.

Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. It has been explored as a treatment option for bacterial keratitis.

Prednisolone can also be used for allergic reactions ranging from seasonal allergies to drug allergic reactions.

Prednisolone can also be used as an immunosuppressive drug for organ transplants.

Prednisolone in lower doses can be used in cases of primary adrenal insufficiency (Addison's disease).

Corticosteroids inhibit the inflammatory response to a variety of inciting agents and, it is presumed, delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation with inflammation.



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Company Info

MOSINTER GROUP LIMITED [China (Mainland)]

sgs ico Offline Showroom in USA

Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

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