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You are here: home  > Pharmaceutical Chemicals API  > Veterinary Medicine API  > Enramycin CAS 12772-37-1 11115-82-5 Enduracidin Enradin Enramicina Enramycinum Enramycinum enduracidin hydrochloride

Enramycin CAS 12772-37-1 11115-82-5 Enduracidin Enradin Enramicina Enramycinum Enramycinum enduracidin hydrochloride 

Payment Terms: T/T,L/C,WU 
Place of Origin: Zhejiang, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: As per request of clients
CAS: 12772-37-1; 11115-82-5
Synonyms: enduracidin hydrochloride; ...
Assay, %: As the standard of 90.0~110...
Arsenic, ppm: ≤ 4
Production Capacity: 100Ton/year
Delivery Date: within 7 days
Melting Point: 234~238℃
Loss on drying, %: ≤ 10
pH: 5.0~8.0
Heavy metals, ppm: ≤ 20

Enramycin or Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicidus. Enramycin is widely used as a feed additive for pigs

Enramycin (CAS: 12772-37-1; 11115-82-5)


ITEM

SPECIFICATION

INDEX

Appearance

Gray or beige powder, Have a special foul-smelling

Comform

Identification

HPLC: The main peak retention time a sample solution and standard solution main peak retention time should be consistent

Comform

particle size

Min.100% pass through 850um

Min.70% pass through 180um

95%

Loss on drying, %

≤ 10

5.5

pH

5.0~8.0

6.3

Heavy metals, ppm

≤ 20

< 20

Arsenic, ppm

≤ 4

< 4

Assay, %

As the standard of 90.0~110.0

102.3(8.18%)



Enramycin or Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicidus. Enramycin is widely used as a feed additive for pigs and chickens to prevent necrotic enteritis induced by Gram-positive gut pathogens.


Mechanism of action

Enramycin acts as an inhibitor of the enzyme, MurG, which is essential for cell wall biosynthesis in Gram-positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibiting this step greatly compromises cell wall integrity leading to cell lysis.


Spectrum of susceptibility

Enramycin has been found to be very effective against Gram-positive gut pathogens, most notably, Clostridium perfringens; a leading cause of necrotic enteritis. The following represents MIC data for a couple of veterinary pathogens.


Clostridium perfringens: 0.05 μg/ml – 1.6 μg/ml

Staphylococcus aureus: 0.013 μg/ml – 0.413 μg/ml


Composition

Standard grade enramycin is composed of two main components called enramycin A and enramycin B. These two components are routinely used as analytical reference standards; however, their activity as individual compounds does not appear to be widely studied or characterized.


Appearance: Gray or beige powder, Have a special foul-smelling

Package: 25KG Drum or As per request of clients

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Company Info

MOSINTER GROUP LIMITED [China (Mainland)]

Offline Showroom in USA

Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

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