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Niclosamide CAS 50-65-7 2 5-dichloro-4-nitrosalicylanilide Niclocide 

Payment Terms: T/T,L/C,WU 
Place of Origin: Zhejiang, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: As per request of clients
CAS: 50-65-7
Molecular weight: 327.1196
Density: 1.616g/cm3
Refractive index: 1.709
Production Capacity: 100Ton/year
Delivery Date: within 7 days
Molecular formula: C13H8Cl2N2O4
Boiling point: 413.905°C at 760 mmHg
Flash point: 204.122°C
Vapour Pressur: 0mmHg at 25°C

Niclosamide (trade name Niclocide) is a teniacide in the anthelmintic family especially effective against cestodes that infect humans and many animals

Niclosamide (CAS: 50-65-7)


ITEM

STANDARD

RESULT

APPEARANCE

YELLOWISH FINE CRYSTALS

WHITE FINE CRYSTALS

IDENTITY

POSITIVE

POSITIVE

CHLORIDES

500 ppm MAX

COMPLIES

5-CHLOROSALICYCLIC ACID

60ppm MAX

COMPLIES

2-CHLORO-4-NITROANILINE

100 ppm MAX

COMPLIES

RELATED SUBSTANCES

0.2% MAX

0.09%

LOSS ON DRYING

0.5 % MAX

0.17%

SULPHATED ASH

0.1% MAX

0.06%

MELTING POINT

227.0~232.0 ℃

229.3~230.4℃

ASSAY

98.0%~101.0%

99.23%

CONCLUSION

THIS STANDARD MEETS ENTERPRISE STANDARD.


Niclosamide (trade name Niclocide) is a teniacide in the anthelmintic family especially effective against cestodes that infect humans and many other animals. It is a salicylanilide compound (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydrobenzamide) also used as a piscicide. While antihelmintics are a drug family used to treat worm infections, niclosamide is used specifically to treat tapeworms and is not effective against other worms such as pinworms orroundworms. It is a chewable tablet taken orally, dosage depending on type of worm and patient's age and/or weight. It is not usually considered the drug of choice for treating cestode infection in humans or animals because of its side effects, though it remains highly effective and is generally inexpensive

Along with oxyclozanide, another tapeworm drug, it has been recently found to display "strong in vivo and in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA)"

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.


Side effects

The medication can have side effects such as abdominal pain, anorexia, diarrhea, and emesis. Rarely, dizziness, skin rash, drowsiness, perianal itching, or an unpleasant taste occur. For some of these reasons, praziquantel is a preferable and equally effective treatment for tapeworm infestation.


Mechanism of action

Niclosamide inhibits glucose uptake, oxidative phosphorylation, and anaerobic metabolism in the tapeworm.


APPEARANCE: YELLOWISH FINE CRYSTALS

Packing: As per request of clients

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Company Info

MOSINTER GROUP LIMITED [China (Mainland)]

Offline Showroom in USA

Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

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