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Ethambutol CAS 74-55-5 2 2'- ethane-1 2-diyldiimino dibutan-1-ol 

Payment Terms: T/T,L/C,WU 
Place of Origin: Zhejiang, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: According to the request of...
Brand Name: MOSINTER
Product Name: Ethambutol
Molecular Weight: 204.3098
Boiling point: 345.3°C at 760 mmHg
Flash point: 113.7°C
Vapour Pressur: 3.9E-06mmHg at 25°C
Production Capacity: 50 Kilogram/Year
Delivery Date: within 7 days
CAS No.: 74-55-5
Molecular Formul: C10H24N2O2
Melting point: 198.5-200.3℃
Density: 0.987g/cm3
Refractive index: 1.477

Ethambutol is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis.

Ethambutol (CAS: 74-55-5) is an antibiotic.


Ethambutol Attribute

Molecular Formula

C10H24N2O2

Molecular Weight

204.3098

Density

0.987g/cm3

Boiling point

345.3°C at 760 mmHg

Refractive index

1.477

Flash point

113.7°C

Vapour Pressur

3.9E-06mmHg at 25°C

Ethambutol Molecular Formula


Synonyms: (+)-2,2-ethylenediiminodibutan-1-ol; 2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol; (2R,2'R)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol


The product is anti-TB effect, commonly used anti-TB medicine resistance in Mycobacterium tuberculosis, the product is still inhibited. Its inhibitory effect was weaker than the small isoniazid, and streptomycin approximation. Other bacteria, fungi invalid.

 

Ethambutol (commonly abbreviated EMB or simply E) is a bacteriostatic antimycobacterial medicine prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis medicine, such as isoniazid, rifampicin and pyrazinamide.

 

Ethambutol is used along with other medications to treat a number of infections, including tuberculosis, Mycobacterium avium complex, and Mycobacterium kansasii.

 

It can cause problems with vision, liver problems and allergies among other side effects. It is pregnancy category C in the United States due to concerns with eye issues and category A in Australia meaning that they did not find evidence of harm after being taken by many pregnant women. It is reasonable to use during breast feeding if required.

 

Medical uses

Ethambutol is used along with other medications to treat a number of infections including: tuberculosis, Mycobacterium avium complex, and Mycobacterium kansasii.[3]

 

Adverse effects

Optic neuritis (hence contraindicated in children below six years of age)

Red-green color blindness

Peripheral neuropathy

Arthralgia

Hepatotoxicity

Hyperuricaemia

Vertical nystagmus

Milk skin reaction

 

Mechanism of action

Ethambutol is bacteriostatic against actively growing TB bacilli. It works by obstructing the formation of cell wall. Mycolic acids attach to the 5'-hydroxyl groups of D-arabinose residues of arabinogalactan and form mycolyl-arabinogalactan-peptidoglycan complex in the cell wall. It disrupts arabinogalactan synthesis by inhibiting the enzyme arabinosyl transferase. Disruption of the arabinogalactan synthesis inhibits the formation of this complex and leads to increased permeability of the cell wall.

 

Pharmacokinetics

It is well absorbed from the gastrointestinal tract and well distributed in body tissues and fluids. 50% is excreted unchanged in urine.


Appearance: white crystalline powder

Packing: 25KG drum

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Company Info

MOSINTER GROUP LIMITED [China (Mainland)]

Offline Showroom in USA

Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

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