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MOSINTER GROUP LIMITED
MOSINTER GROUP LIMITED

China Gimeracil CAS 103766-25-2 GIMERACIL gimestat manufacturer

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Gimeracil CAS 103766-25-2 GIMERACIL gimestat 

Payment Terms: T/T,L/C,WU 
Place of Origin: Zhejiang, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: As per request of clients
Brand: MOSINTER
Appearance: White crystal powder
Molecular Weight: 145.54
Specification: CP/USP/EP
Production Capacity: 200KGS / YEAR
Delivery Date: within 7 days
CAS: 103766-25-2
Purity %≥: 99
Molecular Formula: C5H4ClNO2

Gimeracil inhibits the degradation of fluorouracil by reversibly blocking a dehydrogenase enzyme.

Gimeracil (CAS: 103766-25-2)


Item

Index

Molecular Formula

C5H4ClNO2

Molecular Weight

145.54

Specification

CP/USP/EP

Content

≥99%


The combination drug tegafur/gimeracil/oteracil (trade name Teysuno) is used for the treatment of advanced gastric cancer. It is also being developed for the treatment of hepatocellular carcinoma.

Mechanism of action

Tegafur is the actual chemotherapeutic agent. It is a prodrug of the active substance fluorouracil (5-FU).

Gimeracil inhibits the degradation of fluorouracil by reversibly blocking a dehydrogenase enzyme. This results in higher 5-FU levels and a prolonged half-life of the substance.

Oteracil mainly stays in the gut because of its low permeability, where it reduces the production of 5-FU by blocking the enzyme orotate phosphoribosyltransferase. Lower 5-FU levels in the gut result in a lower gastrointestinal toxicity.

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Company Info

MOSINTER GROUP LIMITED [China (Mainland)]

sgs ico Offline Showroom in USA

Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

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