Offline Showroom in USA
Post Offer Free
MOSINTER GROUP LIMITED
MOSINTER GROUP LIMITED  

Gold Index: 82941

You are here: home  > Pharmaceutical Chemicals API  > Circulatory System Drugs API  > Manidipine hydrochloride CAS 89226-75-5 4-(diphenylmethyl)-1-piperazinyl)ethylmethylester dihydrochloride

Manidipine hydrochloride CAS 89226-75-5 4-(diphenylmethyl)-1-piperazinyl)ethylmethylester dihydrochloride 

Payment Terms: T/T,L/C,WU 
Place of Origin: Sichuan, China (Mainland) 
inquire skype
Add to My Favorites
HiSupplier Escrow
Share |

Product Detail

Model No.: C35H38N4O6 2HCl
Production Capacity: 14T/Year
Delivery Date: within 7 days
CAS: 89226-75-5
Specification: CP/USP/EP
Melting point: 174~182℃
Total impurities: ≤ 1.0%
Loss on drying: ≤6.0%
Means of Transport: Ocean,Land,Air
Packing: According to the customer r...
Brand: MOSINTER
Molecular Formula: C35H38N4O6 2HCl
Molecular Weight: 683.62
Content: 98.0%~101.5%
Cefotaxime: ≤0.5%

Free base for light yellow crystal for first grade. Insoluble in water, soluble in ether, mp125 ~ 128 ℃.

Manidipine hydrochloride (CAS: 89226-75-5)


Item

Index

Molecular Formula

C35H38N4O6・2HCl

Molecular Weight

683.62

Specification

CP/USP/EP


Pharmacologic action

For two hydrogen pyridine class calcium antagonist medicine, high selectivity of blood vessels, step-down effect is strong and durable, can increase renal blood flow, central The effect of dirty is weak. Oral absorption, blood drug concentration peak time 1 ~ 2 hours. In the plasma and protein at a rate of 97%. T1/2 for about 5 hours.

Adaptation disease

Used for high blood pressure, especially in low renin patients with high blood pressure. Also apply for kidney function has been damage.

Untoward effect

The adverse reaction similar nifedipine, accidentally saw a liver or kidney dysfunction, leukopenia, etc.

Appearance 

Free base for light yellow crystal for first grade. Insoluble in water, soluble in ether, mp125 ~ 128 ℃. A homogeneous crystal, alpha model for yellow crystal, insoluble in ethanol, acetone and ethyl ether, soluble in water. Mp157 ~ 163 ℃; Beta is light yellow fine crystal, insoluble in ethanol, ether and acetone, soluble in water. Mp174 ~ 180 ℃.

Application

Calcium channel blockers. Have stronger relaxation arterial smooth muscle, blood vessels, reduce the role of peripheral vascular resistance and arterial pressure. Used in the treatment of essential hypertension, type of low renin hypertension antihypertensive effect is more obvious, and can improve the uric acid metabolism.




bigPhoto
skype Mr. Fedor

Tel: +86-574-89212210
Fax: +86-574-89212215
Mobile: 86- 189 8930 5995
Contact to this supplier

Didn't find what you're looking for? Post Buying Lead or contact HiSupplier Customer Service Center  for help!

Related Search

Find more related products in following catalogs on Hisupplier.com

Company Info

MOSINTER GROUP LIMITED [China (Mainland)]

Offline Showroom in USA

Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

Follow Us: Follow us on facebook Follow us on linkedin

Fedor:   skype

You May Like: