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MOSINTER GROUP LIMITED
MOSINTER GROUP LIMITED

China Vandetanib CAS 443913-73-3 Vandetanib base manufacturer

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Vandetanib CAS 443913-73-3 Vandetanib base 

Payment Terms: T/T,L/C,WU 
Place of Origin: Shandong, China (Mainland) 
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Product Detail

Model No.: C22H24BrFN4O2
Production Capacity: 150kg/year
Delivery Date: ithin 7 days
Brand: MOSINTER
Content: 95%min
Density: 1.406g/cm3
Boiling point: 538.22°C at 760 mmHg
Alias: Vandetanib base
Means of Transport: Ocean,Land,Air
Packing: s per request of clients
Molecular Formula: C22H24BrFN4O2
Specification: CP/USP/EP
Molecular Weight: 475.35
Flashing point: 279.306°C
Name: Vandetanib

Vandetanib is an anti-cancer drug that is used for the treatment of certain tumours of the thyroid gland.

Vandetanib ( CAS: 443913-73-3)


Item

Index

Molecular Formula

C22H24BrFN4O2

Molecular Weight

475.35

Specification

CP/USP/EP

Content

95%min

Vandetanib (INN, trade name Caprelsa) is an anti-cancer drug that is used for the treatment of certain tumours of the thyroid gland. It acts as akinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase. The drug was developed by AstraZeneca.

Approvals and indications

Vandetanib was the first drug to be approved by FDA (April 2011) for treatment of late-stage (metastatic) medullary thyroid cancer in adult patients who are ineligible for surgery.Vandetanib was first initially marketed without a trade name, and is being marketed under the trade name Caprelsa since August 2011.

Contraindications

In patients with moderate and severe hepatic impairment, no dosage for vandetanib has been recommended, as its safety and efficacy has not been established yet.Vandetanib is contraindicated in patients with congenital long QT syndrome.

Adverse effects

Common side effects include abdominal pain and diarrhoea, rashes, prolonged QT interval, hypertension, headache, and fatigue.

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Company Info

MOSINTER GROUP LIMITED [China (Mainland)]

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Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

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