Offline Showroom in USA
Post Offer Free

Gold Index: 82941

You are here: home  > Indicator Tracer Agent  > Sodium diethyldithiocarbamate CAS148-18-5 ditiocarb sodium Sodium Diethyl Dithiocarbamate

Sodium diethyldithiocarbamate CAS148-18-5 ditiocarb sodium Sodium Diethyl Dithiocarbamate 

Payment Terms: T/T,L/C,WU 
Place of Origin: Shandong, China (Mainland) 
inquire skype
Add to My Favorites
HiSupplier Escrow
Share |

Product Detail

Means of Transport: Ocean,Land,Air
Packing: According to customer requi...
Brand Name: MOSINTER
Molecular mass: 171.25
Boiling point: 176.4°C at760mmHg
solubility in water: >=10 G/100 ML AT 14 ºC
Production Capacity: 10 Ton/Year
Delivery Date: within 7 days
CAS No.: 148-18-5
Molecular Formula: C5H10NNAS2
Melting point: 95 °C
Density: 1.086g/cm3
Alias: ditiocarb sodium

The effect of diethyldithiocarbamate of chelating zinc inhibits metalloproteinases

Sodium diethyldithiocarbamate (CAS: 148-18-5)




Melting point ℃


Boiling Point ℃


Flash Point ℃




Sodium diethyldithiocarbamate is the organosulfur compound with the formula NaS2CN(C2H5)2.


This salt is obtained by treating carbon disulfide with diethylamine in the presence of sodium hydroxide:

CS2 + HN(C2H5)2 + NaOH → NaS2CN(C2H5)2 + H2O

Other dithiocarbamates can be prepared similarly from secondary amines and carbon disulfide. They are used as chelating agents for transition metal ions and as precursors to herbicides and vulcanization reagents.

Oxidation to thiuram disulfide

Oxidation of sodium diethyldithiocarbamate gives the disulfide, also called a thiuram disulfide (Et = ethyl):

2 NaS2CNEt2 + I2 → Et2NC(S)S-SC(S)NEt2 + 2 NaI

This disulfide is marketed as an anti-alcoholism drug under the labels Antabuse and Disulfiram. Chlorination of the above-mentioned thiuram disulfide affords the thiocarbamoyl chloride.

Ligand bonding

The diethyldithiocarbamate ion chelates to many "softer" metals via the two sulfur atoms. Other more complicated bonding modes are known including binding as unidentate ligand and a bridging ligand using one or both sulfur atoms.

Spin trapping of nitric oxide radicals

Complexes of Dithiocarbamates with iron provide one of the very few methods to study the formation of nitric oxide (NO) radicals in biological materials. Although the lifetime of NO in tissues is too short to allow detection of this radical itself, NO readily binds to iron-dithiocarbamate complexes. The resulting mono-nitrosyl-iron complex (MNIC) is stable, and may be detected with Electron Paramagnetic Resonance (EPR) spectroscopy.

In cancer

The effect of diethyldithiocarbamate of chelating zinc inhibits metalloproteinases, which in turn prevents the degradation of extracellular matrix, which is an initial step in cancermetastasis and angiogenesis.


Diethyldithiocarbamate inhibits superoxide dismutase, which can both have antioxidant and oxidant effects on cells, depending on the time of administration.

In metabolism

Diethyldithiocarbamate has been described to interfere with glucocorticoid metabolism, by inhibiting the activity of the enzyme 11beta-hydroxysteroid dehydrogenase type 2, which converts cortisol to cortisone.


skype Mr. Fedor

Tel: +86-574-89212210
Fax: +86-574-89212215
Mobile: 86- 189 8930 5995
Contact to this supplier

Didn't find what you're looking for? Post Buying Lead or contact HiSupplier Customer Service Center  for help!

Related Search

Find more related products in following catalogs on

Company Info


Offline Showroom in USA

Business Type:Manufacturer, Trading Company
City: Ningbo
Province/State: Zhejiang
Country/Region: China (Mainland)

Follow Us: Follow us on facebook Follow us on linkedin

Fedor:   skype

You May Like: